Workshop Molecular Modelling on CLRs/binding sites

VU Amsterdam, December 8-9 2008

Session 1: Supporting technologies:

(presentation to provoke discussions and make inventory of available skills and tools)

1. What did we learn from X-ray analysis so far? by  Titia Sixma and Guus Smit. Login for presentation.
2. About sequence alignments of CLR by Chris Ulens, Andy Thompson, Margot Ernst and Christoph Kluck. Login for presentation.
3. Homology modelling of CLR by Dimitry Kuzmin and Victor Tsetlin. Login for presentation.
4. Biophysical screening technologies within Neurocypres by Georgios Spyroulias and Maria Lindgren (NMR and SPR). Login for presentation.

Session 2: 5HT3 receptors

1. Overview of 5HT3 receptor research within Neurocypres by Sarah Lummis and others. Login for presentation.

Session 3: Glycine Receptors Room S111

1. Overview of Glycine receptor research within Neurocypres by  Christoph Kluck and others. Login for presentation.

Session 4: Parallel round table discussions (alternative: tour of lab facilities with Jacqueline Muijlwijk)

1. 5HT3 receptors in the Neurocypres context: defining projects: Round table discussions 1
2. Glycine receptors in the Neurocypres context: defining projects: Round table discussions 2

Session 5: GABA receptors

1. Overview of GABA receptor research within Neurocypres by Werner Sieghart (Med. Univ. Vienna). Login for presentation.

Session 6: Parallel activities

1. GABA(a) receptors in the Neurocypres context: defining projects: Round table discussions 3 (will merge with other talks asap). Login for presentation.
2. Modelling of prokaryotic LGIC interaction by Dimitry Kuzmin and Victor Tsetlin. Login for presentation.
3. Molecular dynamics studies by Georgios Spyroulias. Login for presentation.
4. Ligand-receptor screening methods by Prakash Rucktoaa and Atilla Akdemir. Login for presentation.
5. Medicinal Chemistry Opportunities within Neurocypres by Mark Verheij and Jacqueline van Muijlwijk. Login for presentation.